GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs703842 | 1 | rs11172342 | chr12:58187758 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -3.95 | 9.44E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172343 | chr12:58188157 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.37 | 1.6E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172343 | chr12:58188157 | TSFM | chr12:58176536-58191367:+ | -0.38 | -6.72 | 6.57E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172343 | chr12:58188157 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -3.95 | 9.44E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | FAM119B | chr12:58166383-58176323:+ | 0.29 | 4.54 | 7.64E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | TSFM | chr12:58176536-58191367:+ | -0.36 | -6.42 | 3.97E-10 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.14 | 4.3E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | FAM119B | chr12:58166383-58176323:+ | 0.29 | 4.49 | 9.52E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | TSFM | chr12:58176536-58191367:+ | -0.39 | -6.95 | 1.6E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.17 | 3.76E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172351 | chr12:58213485 | FAM119B | chr12:58166383-58176323:+ | 0.3 | 4.62 | 5.23E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172351 | chr12:58213485 | TSFM | chr12:58176536-58191367:+ | -0.39 | -6.84 | 3.13E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172351 | chr12:58213485 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.12 | 4.69E-5 | Multiple sclerosis |
| BLCA | cis | rs2404602 | 1 | rs1117367 | chr15:76872330 | SCAPER | chr15:76640529-77197744:- | -0.2 | -4.47 | 1.03E-5 | Blood metabolite levels |
| BLCA | cis | rs56322409 | 1 | rs11188394 | chr10:97365458 | ENTPD1 | chr10:97471536-97637022:+ | 0.19 | 4.89 | 1.51E-6 | Blood metabolite levels |